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HPRCA Laboratory Assistant (Chemistry & Toxicology) Syllabus

Exam Conducting Body: Himachal Pradesh Rajya Chayan Aayog (HPRCA)
Post: Laboratory Assistant (Chemistry & Toxicology)
Level: Graduation Level

1. Subjects up to Graduation Level

A. Forensic Science

i) General Forensic Science

Definition, History and Development of Forensic Science
Principles and Scope of Forensic Science
Organizational Structure of Forensic Science Laboratories/Institutions in India
Crime Scene Management
Types of Evidence and Chain of Custody
Integrity of Evidence
Standard Operating Instructions for Collection of Physical Evidence
Digital Evidence from Crime Scene
Quality Control, Quality Assurance
Frye Standard and Daubert Standard

ii) Toxicology

Definition and Classification of Poisons (Based on Origin)
Types of Poisoning
Routes of Administration: Absorption, Distribution, Metabolism and Extraction
Lethal Dose (LD₅₀)
Signs and Symptoms of Common Poisons
Alkaloids: Definition, Classification and Properties
Preliminary Screening Methods for Drugs of Abuse

B. Chemistry

i) Inorganic Chemistry

Atomic Structure: Bohr’s Theory, Dual Nature, de Broglie Relation, Heisenberg Uncertainty Principle, Schrödinger Equation, Atomic Orbitals, Quantum Numbers, Electronic Configuration
Chemical Bonding: Ionic & Covalent Bonding, Born–Haber Cycle, VSEPR Theory, Hybridization, Molecular Orbital Theory, VB vs MO Approach
Hydrogen: Isotopes, Ortho & Para Hydrogen, Hydrides, Heavy Water, Hydrogen Bonding
S-Block Elements: Periodicity, Properties, Solvation, Complex Formation
P-Block Elements: Hydrides, Oxides, Oxyacids, Halides, Boron, Carbon, Nitrogen, Phosphorus Compounds
Noble Gases: Occurrence, Compounds, Xenon Fluorides
Lanthanoids & Actinoids: Electronic Configuration, Oxidation States, Lanthanide Contraction
Chromatography: Paper Chromatography, TLC, Ion Exchange Chromatography
Crystal Field Theory: CFSE, Octahedral & Tetrahedral Complexes
Acids & Bases: Arrhenius, Bronsted, Lewis, HSAB Concept
Bioinorganic Chemistry: Metalloporphyrins, Haemoglobin & Myoglobin

ii) Organic Chemistry

Fundamentals: Inductive Effect, Resonance, Hyperconjugation, Reaction Intermediates
Stereochemistry: Optical & Geometrical Isomerism, R/S, E/Z Nomenclature
Alkanes, Alkenes, Alkynes: Preparation and Reactions
Aromatic Hydrocarbons: Benzene, Electrophilic Substitution, Friedel–Crafts Reaction
Alkyl & Aryl Halides: SN₁, SN₂, Elimination Reactions
Alcohols, Phenols & Ethers
Aldehydes & Ketones: Aldol, Cannizzaro, Wittig Reaction
Carboxylic Acids & Derivatives
Amines & Diazonium Salts
Polynuclear Hydrocarbons
Synthetic Dyes
Carbohydrates: Glucose, Fructose, Disaccharides, Polysaccharides
Amino Acids, Peptides & Proteins
Nucleic Acids: DNA, RNA, Genetic Code
Spectroscopy: UV-Visible, IR, NMR, Raman, Molecular Spectroscopy

iii) Physical Chemistry

Kinetic Theory of Gases
Liquids: Surface Tension, Viscosity
Solids: Crystal Systems, Bragg’s Law, X-ray Diffraction
Solutions: Raoult’s Law, Azeotropes, Nernst Distribution Law
Chemical Kinetics
Phase Equilibrium: Gibbs Phase Rule
Electrochemistry: EMF, Nernst Equation, Conductance
Chemical Energetics & Thermodynamics
Chemical & Ionic Equilibrium

2. General Awareness

General Knowledge: General Knowledge including General Knowledge of Himachal Pradesh.
Current Affairs: National, International and Himachal Pradesh related current events.
Everyday Science: Basic concepts of Physics, Chemistry and Biology used in daily life.
Logical Reasoning: Analogy, series, coding-decoding, direction sense, blood relations, syllogism and basic reasoning aptitude.
Social Science (10^th Standard): History, Geography, Civics and Economics as per Class 10 level.
General English (10^th Standard): Grammar, vocabulary, comprehension, sentence correction and basic usage.
General Hindi (10^th Standard): व्याकरण, शब्दावली, वाक्य सुधार, गद्यांश एवं सामान्य हिंदी ज्ञान।

📌 Exam Level: Graduation (Chemistry & Toxicology) + 10th Level (General Awareness)

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